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[] Although a recent review concluded that the lamotrigine does not increase the incidence of hypomania or manic switches,[] cases of lamotrigine-induced manic switches in patients with bipolar disorder have been reported. 5mg Your second decrease would be half a 200mg tablet (100mg) plus 1 50mg tablet plus half of a 50mg tablet = 175mg. I’m on 150mg and it’s very effective. Taking Mirapex; he wants me to get off that too. 2 level 1 radartemisia · 3 yr. Certainly some people will turn up that need more Lamictal (genetics plays a big role in metabolizing it) and then there is no problem. 5 mg - (yes a tenth part of the normal initial dose!! To avoid an increased risk of rash, the recommended maintenance dosage range of LAMICTAL XR as monotherapy is 250 to 300 mg given once daily. Low dose Lamictal for OCD and depression? Patience On Lamictal for 6 years at 150 mg/d. Cardiovascular toxicities occurred primarily in adult patients (threshold >25 mg/L).. 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